Nobody wants to play “hunt the interesting bit” with your photos! So get in close, and fill the frame. Remember:
“If it’s not good enough, you’re not close enough”
[Good advice for all except war photographers and wild animal specialists]
Or, make a point of not filling the frame, but giving the picture some “positive space” – a tricky thing to define, but examples should make things clearer. The skill is knowing which to go for under what circumstances!